Pesquisa sobre:
14-3-3 PROTEINS
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DeCS
Descritor
Inglês
:
14-3-3 Proteins
Descritor
Espanhol
:
Proteinas 14-3-3
Descritor
Português
:
Proteínas 14-3-3
Categoria:
D12.644.360.024.050
D12.776.157.057.002
D12.776.476.024.050
Definição
Inglês
:
A large
family
of signal-transducing adaptor
proteins
present in wide variety of eukaryotes. They are
PHOSPHOSERINE
and
PHOSPHOTHREONINE
binding
proteins
involved in important cellular processes including
SIGNAL TRANSDUCTION
;
CELL CYCLE
control
;
APOPTOSIS
; and cellular stress responses.
14-3-3 proteins
function by interacting with other signal-transducing
proteins
and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the
proteins.
Nota Histórica
Inglês
:
2005(1981)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
38740
Identificador Único:
D048948
Ocorrência na BVS
:
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